The Chinese video-sharing platform is the only app not owned by Facebook to make the global top five of downloads.
In its home country, TikTok's owner ByteDance also holds the top spot with the Chinese language video app Douyin.
TikTok's continued popularity emerged even after former US President Donald Trump tried to ban it in America.
Facebook-owned apps have held the top spot since the survey started in 2018 and the company still dominated the chart.
Mark Zuckerberg's social media giant accounted for the rest of the top five with Facebook's flagship app as well as WhatsApp, Instagram and Facebook Messenger all making an appearance.